Archive for July, 2008

For McCain, an uncomfortable question about Viagra funding

Sunday, July 27th, 2008

On CNN last night, long-time GOP political strategist Ed Rollins called it the most uncomfortable response to a question that he’s seen in his more than 40 years in politics:

Republican presidential candidate John McCain was asked Wednesday if he agrees with one of his advisers, Carly Fiorina, that it’s unfair for health insurers to pay for men to get Viagra but not for women to get birth control pills.

CNN has video of the exchange McCain had with a reporter.

“I certainly do not want to discuss that issue,” McCain says at the opening.

“I don’t know enough about it to give you an informed answer,” he adds after a long pause.

Introduction to How Viagra Works

Wednesday, July 16th, 2008

Viagra is one of the best-known drugs of all time:

  • Google lists over 17 million Web pages that use the word “Viagra.” For comparison, Google lists only 3.3 million pages containing the word “aspirin” and only 936,000 containing the word “Tylenol.”
  • Billions of spame-mail messages advertise Viagra every day. There is so much Viagra spam, in fact, that Pfizer (the maker of Viagra) has a page addressing the problem, called Avoid Fake Viagra, prominently listed on Viagra.com.
  • Pfizer has spent untold millions of dollars advertising Viagra, so you see advertisements for the drug constantly on TV.
  • Pfizer claims on its Web site that nine Viagra pills are dispensed every second — nearly 300 million tablets per year.
  • The name recognition of Viagra is so good that nearly every adult in America has heard of the drug and can tell you what it does.

What Viagra does is simple: When it works as intended, Viagra causes a man who is sexually stimulated to get an erection.

How does Viagra do that? And why does Viagra work only if the man is sexually stimulated? For that matter, what causes an erection in the first place? In this article, we’ll answer all of those questions and more.

This is actually a fascinating story — it involves the technology of the human body and the techniques that scientists use to control different parts of the body with drugs. And in the case of Viagra, the story starts with the technology of the penis…

Watermelon Has Viagra-Like Effect, Say Scientists

Thursday, July 3rd, 2008

A slice of cool, fresh watermelon is a juicy way to top off a Fourth of July cookout and one that researchers say has effects similar to Viagra — but don’t necessarily expect it to keep the fireworks all night long.

Watermelons contain an ingredient called citrulline that can trigger production of a compound that helps relax the body’s blood vessels, similar to what happens when a man takes Viagra, said scientists in Texas, one of the nation’s top producers of the seedless variety.

Found in the flesh and rind of watermelons, citrulline reacts with the body’s enzymes when consumed in large quantities and is changed into arginine, an amino acid that benefits the heart and the circulatory and immune systems.

“Arginine boosts nitric oxide, which relaxes blood vessels, the same basic effect that Viagra has, to treat erectile dysfunction and maybe even prevent it,” said Bhimu Patil, a researcher and director of Texas A&M’s Fruit and Vegetable Improvement Center. “Watermelon may not be as organ-specific as Viagra, but it’s a great way to relax blood vessels without any drug side effects.”

Todd Wehner, who studies watermelon breeding at North Carolina State University, said anyone taking Viagra shouldn’t expect the same result from watermelon.

“It sounds like it would be an effect that would be interesting but not a substitute for any medical treatment,” Wehner said.

The nitric oxide can also help with angina, high blood pressure and other cardiovascular problems, according to the study, which was paid for by the U.S. Department of Agriculture.

More citrulline — about 60 percent — is found in watermelon rind than in the flesh, Patil said, but that can vary. But scientists may be able to find ways to boost the concentrations in the flesh, he said.

Citrulline is found in all colors of watermelon and is highest in the yellow-fleshed types, said Penelope Perkins-Veazie, a USDA researcher in Lane, Okla.

She said Patil’s research is valid, but with a caveat: One would need to eat about six cups of watermelon to get enough citrulline to boost the body’s arginine level.

“The problem you have when you eat a lot of watermelon is you tend to run to the bathroom more,” Perkins-Veazie said.

Watermelon is a diuretic and was a homeopathic treatment for kidney patients before dialysis became widespread.

Another issue is the amount of sugar that much watermelon would spill into the bloodstream –a jolt that could cause cramping, Perkins-Veazie said.

Patil said he would like to do future studies on how to reduce the sugar content in watermelon.

The relationship between citrulline and arginine might also prove helpful to those who are obese or suffer from type-2 diabetes. The beneficial effects — among them the ability to relax blood vessels, much like Viagra does — are beginning to be revealed in research.

Citrulline is present in other curcubits, like cucumbers and cantaloupe, at very low levels, and in the milk protein casein. The highest concentrations of citrulline are found in walnut seedlings, Perkins-Veazie said.

“But they’re bitter and most people don’t want to eat them,” she said.